- Jules Verne -
“Science, my lad, is made up of mistakes, but they are mistakes which it is useful to make, because they lead little by little to the truth.”
PUBLICATIONS
2017 Draughn, G.L., Allen, C.L., Routh, P.A., Stone, M.R., Kirker, K.R., Boegli, L, Schuchman, R.M., Linder, K.E., Baynes, R.E., James, G, Melander, C, Pollard, A, and Cavanagh, J. Evaluation of a 2-aminoimidazole variant as adjuvant treatment for dermal bacterial infections. Drug Des. Dev. Ther., 153-162.
2016 Drake, E.J., Miller, B.R., Shi, C., Tarrasch, J.T., Sundlov, J.A., Allen, C.L., Skiniotis, G., Aldrich, C.A. and Gulick, A.M. Structures of Two Distinct Conformations of holo-Nonribosomal Peptide Synthetases. Nature, 529, 235–238.
2015 Kholodar, S.A., Allen, C.L., Gulick, A.M. and Murkin, A.S. The Role of Phosphate in a Multistep Enzymatic Reaction: Reactions of the Substrate and Intermediate in Pieces. J Am Chem Soc, 137 (7), 2748-2756.
2014 Allen, C.L., and Gulick, A.M. Structural and bioinformatic characterization of an Acinetobacter baumannii type II carrier protein. Acta Cryst, D70, 1718-1725.
2014 Kholodar, S.A., Tombline, G., Liu, J., Tan, Z., Allen, C.L., Gulick, A.M., and Murkin, A.S. Alteration of the Flexible Loop in 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase Boosts Enthalpy-Driven Inhibition by Fosmidomycin. Biochemistry, 53 (21), 3423-3431.
2005 Parish, D.A., Zhou, Z., Allen, C.L., Day, C.S. and King, B.S. A convenient method for the synthesis of N-hydroxyureas. Tetrahedron Letters, 46, 8841-8843.
Academic Publications
Publications Awaiting Submission
2017 Allen, C.L., Feldmann, E.A., Bobay, B.G., Stevens, M., Lucas J.L., Melander, R.J. , Zeng, D., Melander, C., and Cavanagh, J. Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2-aminoimidazole- based compounds. (in preparation)
2017 Allen, C.L., Draughn, G.L., Feldmann, E.A., Thompson, R.J., Schuchman, R.M., Wilder, P.T., Adipietro, K.A., Duff, K., Zimmer, D.B., Stowe, S.D., Cavanagh, J. A deeper investigation into the (non)interaction between calbindin D28k and caspase-3. (in preparation)
2017 Allen, C.L., Hover, B.M, Nicely, N.I. and McCafferty, D.G. The Crystal Structures of Both Unbound and Substrate-Bound Forms of E. coli Anhydromuramic Acid Kinase In Support of A Concerted Mechanism. (in preparation)
2017 Allen, C.L., Clancy, K.M. and McCafferty, D.G. The Transition State Model and Product Complexes of E. coli Anhydromuramic Acid Kinase and the Mechanistic Implications. (in preparation)